If any team lost 4 of their 6 most influential/in-form players at once they'd struggle.
Cooper

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Souttar

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Souza

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Arblaster

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Hamer

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Campbell

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Obviously arguable in terms of most influential, but I think it's fair to say they've been most people's top 6 so far.
Other mentions may be...

Anel (was missing for 3 games during the same period)

Moore (was injured during the same period)

Rak-Sakyi (also injured during the same period)

O'Hare (can apparently run forever)

Burrows (again, thankfully appears to be quite stable)
I reckon most people would pick the names on this list as our best performing 11 players so far this season...and we've only had half of them available (at most) for a lot of recent weeks.
Add in that Seriki, RND & Shackleton have also been injured...Peck is only 20 years old and had knee surgery last year...Tom Davies is just back from a monumental injury debacle...Brewster is made of glass.
Any team would struggle under those circumstances